Articles citing this paper
Interrogating Fragments Using a Protein Thermal Shift Assay
Róisín M. McMahon A D , Martin J. Scanlon B C and Jennifer L. Martin A DA Division of Chemistry and Structural Biology, Institute for Molecular Bioscience, University of Queensland, St Lucia, Qld 4072, Australia.
B Medicinal Chemistry and Drug Action, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, Vic. 3052, Australia.
C ARC Centre for Coherent X-Ray Science, Monash University, Parkville, Vic. 3052, Australia.
D Corresponding authors. Email: r.mcmahon@imb.uq.edu.au; j.martin@imb.uq.edu.au
![]() Róisín M. McMahon is a post-doctoral researcher working with Professor Jennifer L. Martin at the Institute for Molecular Bioscience, University of Queensland. Her research interests are in the application of structural biology techniques, particularly macromolecular crystallography, for protein structure–function investigations of cell surface and integral membrane proteins, with a complementary interest in the structural characterisation of druggable targets. She read Natural Sciences at Cambridge University and holds a D.Phil. from Oxford University. |
![]() Martin J. Scanlon is an Associate Professor in the Monash Institute for Pharmaceutical Sciences at Monash University. His research focuses on the characterisation of drug–protein interactions and the use of fragment-based approaches to identify novel ligands for proteins. |
![]() Jennifer L. Martin is an ARC Australian Laureate Fellow at the Institute for Molecular Bioscience, University of Queensland. Her research interests focus on protein structure and drug design, targeting infection, inflammation, and diabetes. She trained as a pharmacist in Victoria, was awarded a D.Phil. from Oxford University and spent her post-doctoral years at Rockefeller University. |
Australian Journal of Chemistry 66(12) 1502-1506 https://doi.org/10.1071/CH13279
Submitted: 31 May 2013 Accepted: 29 July 2013 Published: 5 September 2013