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Microwave-Assisted Tandem Processes for the Synthesis of N-Heterocycles

Mohammed Abid A , Béla Török B and Xudong Huang A C
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A Conjugate and Medicinal Chemistry Laboratory, Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Brigham and Women’s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.

B Department of Chemistry, University of Massachusetts Boston, 100 Morrissey Boulevard, Boston, MA 02125, USA.

C Corresponding author. Email: xhuang3@partners.org




Dr Xudong Huang is an Assistant Professor of Radiology, Harvard Medical School, and the Director for Conjugate and Medicinal Chemistry Laboratory, Division of Nuclear Medicine and Molecular Imaging at the Radiology Department of Brigham and Women’s Hospital (BWH)/Harvard Medical School. Dr Huang received his Ph.D. from MIT (Nuclear Science and Engineering). He performed his post-doctoral work at Massachusetts General Hospital (MGH)/Harvard Medical School. His current research thrust is to rapidly screen and design, synthesize, and characterize large numbers of targeted theranostic compounds for human diseases such as neurological disorders, cancer, diabetes, and cardiovascular diseases.



Béla Török graduated with a BS/MS and later Ph.D. in Chemistry (under the supervision of Árpád Molnár) at the University of Szeged, Hungary. He spent a post-doctoral year with Nobel Laureate George A. Olah at the Loker Hydrocarbon Research Institute, University of Southern California, in Los Angeles. Later, he joined the group of Mihály Bartók as a senior research associate at the Hungarian Academy of Sciences. In 2000, he returned to Los Angeles as a senior research associate in Professor Olah’s group. In 2002, he became an assistant professor at the Michigan Technological University. In 2005, he moved to the University of Massachusetts in Boston as an associate professor, where he currently works. His major research interest lies in the area of development of new environmentally benign synthetic methodologies, mostly using catalysis as a major tool. His current efforts focus on the combination of heterogeneous catalysis and microwave energy in synthesis.



Mohammed Abid began his scientific career in Boston. He obtained his Ph.D. (under supervision of Professor Béla Török) at the University of Massachusetts, Boston. Following his Ph.D. in 2007, he joined as a post-doctoral fellow the laboratory of Professor Xudong Huang at the Brigham and Women’s Hospital and Harvard Medical School. His current research interests include the synthesis of novel therapeutic agents having potential applications in diagnosis and treatment of cancer, diabetes, and Alzheimer’s disease.

Australian Journal of Chemistry 62(3) 208-222 https://doi.org/10.1071/CH08474
Submitted: 1 November 2008  Accepted: 10 February 2009   Published: 20 March 2009



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