Mycalone: a New Steroidal Lactone From a Southern Australian Marine Sponge, Mycale sp.

Abstract

Mycalone (1), a new steroid incorporating a novel six- membered lactone side chain, has been isolated fram a southern Australian marine sponge, Mycale sp. The gross structure for mycalone (1) was secured by spectroscopic analysis, and the stereochemistry established by a single-crystal X-ray structure determination.