Reactions of Chelated β-Functionalized Amino Acids With Thionyl Chloride

Abstract

A variety of bis (ethane-1,2-diamine)cobalt(III) complexes containing chelated β-functionalized amino acids have been treated with SOCl₂ in dimethylformamide. These compounds undergo β-elimination reactions to give chelated enamines followed by either rearrangement to the related imine complexes or further reactions with SOCl₂ to give chelated isothiazole-3-carboxylato complexes. Mechanisms are proposed for the reactions.