An Alternative Synthesis of N -Acetyl-4-deoxyneuraminic Acid
Hua Chee Ooi, Sebastian M. Marcuccio and W. Roy Jackson
Australian Journal of Chemistry
52(10) 937 - 940
Published: 1999
Abstract
A synthesis of N-acetyl-4-deoxyneuraminic acid (11) from N-acetylneuraminic acid (1) via the corresponding unsaturated derivative (4) is described. This synthesis of the important N-acetylneuraminic acid aldolase (EC 4.1.3.3) inhibitor overcomes several difficulties associated with two previously published syntheses.https://doi.org/10.1071/CH99117
© CSIRO 1999
