The Stereochemistry of Organometallic Compounds. XXXII. Hydrocyanation of Derivatives of Amino Alkynes

Abstract

The hydrocyanation of a range of amino alkyne derivatives has been studied by using nickel-based catalyst systems. The phthalimido derivatives have been shown to give good yields of unsaturated cyano amine derivatives, and some of these have been converted into both saturated and unsaturated amino acids.