Heterocyclic Variants of the Purine System. I. Derivatives of Thiazolo[5,4-e]-1,2,4-Triazine

Abstract

Derivatives of the thiazolo [5,4-e]-1,2,4-triazine ring system were prepared from appropriate 6-acylamino-1,2,4-triazin-5(2H)-ones by thiation and cyclization with phosphorus pentasulfide. 5-Methylthio-1,2,4-triazin-6-amines also gave thiazolo [5,4-e]-1,2,4-triazine derivatives when treated with carbon disulfide or phenyl isothiocyanate.