Pyrimidine N-oxides. VI. The ionization constants of Pyrimidine-2,4-diamine N-oxides

Abstract

The ionization constants of some pyrimidine-2,4-diamines and their N-oxides, including the drugs 'trimethoprim' and 'minoxidil', are reported. The syntheses of several pyrimidine-2,4-diamine N-oxides are described.