The reaction of alkyllithium reagents with Furan-3-carboxylic acid. A synthesis of 4-(Furan-3'-yl)-1-methylbutyltriphenylphosphonium iodide

Abstract

The ketones, 4-benzyloxy-1-(furan-3'-yl)pentan-1-one and 4-benzyloxy-1-(furan-3'-yl)butan-1-one, have been prepared by generating the required alkyllithium reagent in the presence of lithium furan-3-carboxylate. The latter ketone has been transformed to 4-(furan-3'- yl)-1-methylbutyltri-phenylphosphonium iodide.