Catalysis by α-substituted pyridines in the hydrolysis of aryl acetates and acetic anhydride

Abstract

Results for the hydrolysis of p-nitrophenyl acetate, 2,4-dinitrophenyl acetate and acetic anhydride, catalysed by various substituted 2-amino- and 2-methyl-pyridines, are reported. The results seem consistent with nucleophilic catalysis throughout, contrary to some literature reports.