The synthesis of the N-methyl analogue of S-adenosylmethionine; N.M.R. observation of diastereomers

Abstract

The N-methyl analogue (1; X = N-Me) of S-adenosylmethionine has been synthesized; the intermediates and the end-product are racemic at the amino acid α-carbon, and show diastereomeric splitting in their ¹³C n.m.r. spectra.