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Australian Journal of Chemistry Australian Journal of Chemistry Society
An international journal for chemical science
RESEARCH ARTICLE

N-(Carboxymethyl)-N-[2-(2,6-diisopropylphenyl)amino]-2-oxoethylglycine and analogues: Synthesis and characterization

MP Best, RH McKeown and O Wong

Australian Journal of Chemistry 35(11) 2371 - 2375
Published: 1982

Abstract

N-(Carboxymethyl)-N-[2-(2,6-diisopropylphenyl)amino]-2-oxoethylglycine (DIS-IDA)* (2a) and two analogues have been successfully synthesized. The synthesis involved a modified one-pot reaction with specific reaction conditions to maximize yields. A general procedure for the isolation of the products has been set out and the stability of compounds (2) is briefly discussed. Characterization is reported with a view for use with 99mTc as radiopharmaceuticals.

https://doi.org/10.1071/CH9822371

© CSIRO 1982

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