Novel nano-ZnO/alginate films with potential antibacterial properties
Shuping Zhang
A * , Yue Gao A , Yankai Li A , Li Li A and Huiling Wu A
+ Author Affiliations
- Author Affiliations
A School of Materials and Chemistry, University of Shanghai for Science and Technology, Shanghai 200093, P. R. China.
Australian Journal of Chemistry 75(10) 787-794 https://doi.org/10.1071/CH22040
Submitted: 25 February 2022 Accepted: 11 July 2022 Published: 10 November 2022
© 2022 The Author(s) (or their employer(s)). Published by CSIRO Publishing.
Abstract
This study was conducted to develop nano-ZnO/alginate films with good mechanical properties and potent antibacterial activity as a new kind of wound dressing. The nano-ZnO/alginate films were prepared by a solvent casting method. Meanwhile, the thickness, water absorption and water vapour permeability (WVP) of alginate films with different alginate and glycerol contents were evaluated. Results show a positive influence of alginate and glycerol on the thickness and moisture sorption properties. In addition, the WVP of the films first increased and then decreased as the glycerol content increased, but it was not significantly affected by the concentration of alginate. Finally, the antimicrobial properties of the films were tested against E. coli and S. aureus, the results revealed that when the nano-ZnO content based on the film-forming solution was 0.25% (w/v) the films exhibited strong activity against both pathogens with a reduction in CFU of 99.48% for E. coli and 99.02% for S. aureus. The outcome of this study indicated that the nano-ZnO/alginate films could be used as a new kind of wound dressing.
Keywords: alginate, antibacterial activity, composite fiber, films, nano-ZnO, solvent-casting, water absorbency, wound dressing.
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