Steroidal Saponins Isolated from an Australian Yam Dioscorea sp.
Victoria L. Challinor A , David M. Smith A and James J. De Voss A B
+ Author Affiliations
- Author Affiliations
A School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Qld 4072, Australia.
B Corresponding author. Email: j.devoss@uq.edu.au
Australian Journal of Chemistry 64(5) 545-549 https://doi.org/10.1071/CH11056
Submitted: 31 January 2011 Accepted: 5 March 2011 Published: 30 May 2011
Abstract
Phytochemical characterization of the rhizome of an Australian species of Dioscorea, acquired as Dioscorea transversa R Br. but botanically identified as Dioscorea sp., led to the isolation of two steroidal saponins. The major constituent 1β-hydroxyprotogracillin (1) was previously unknown while the minor one was identified as protogracillin (2). The structure and stereochemistry of 1 were elucidated using a combination of MS studies, 1D and 2D NMR experiments and chemical degradation.
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