The Synthesis of Potential DNA Intercalators. 2. Tri- and Tetra-Cyclic Heterocycles*

Ali Reza Molla Ebrahimlo; Jabbar Khalafy; Rolf H. Prager

doi:10.1071/CH08370

RESEARCH ARTICLE

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The Synthesis of Potential DNA Intercalators. 2. Tri- and Tetra-Cyclic Heterocycles*

Ali Reza Molla Ebrahimlo ^A , Jabbar Khalafy ^A ^C and Rolf H. Prager ^B

+ Author Affiliations

- Author Affiliations

^A Chemistry Department, Urmia University, Urmia 57159, Iran.

^B Chemistry Department, Flinders University of South Australia, GPO Box 2100, Adelaide, SA 5001, Australia.

^C Corresponding author. Email: j.khalafi@mail.urmia.ac.ir

Australian Journal of Chemistry 62(2) 126-132 https://doi.org/10.1071/CH08370
Submitted: 1 September 2008 Accepted: 19 December 2008 Published: 19 February 2009

Abstract

The reaction of 1,4-dichlorophthalazine and 2,3-dichloroquinoxaline with some isoxazolones gave their mono- and bis-isoxazolinyl derivatives. The base-catalyzed rearrangement of these derivatives afforded the corresponding tri- and tetracyclic heterocycles.

^* Part 1. A. R. Molla Ebrahimlo, J. Khalafy, Arkivoc 2008, xiii, 65.

Acknowledgements

We are grateful to the University of Urmia for support of the present work. We also thank the Chemistry Department of Flinders University for the gift of chemicals.

References

The Synthesis of Potential DNA Intercalators. 2. Tri- and Tetra-Cyclic Heterocycles*

Abstract

Acknowledgements

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