Diterpenoid Hydroperoxides from the Far-Eastern Brown Alga Dictyota dichotoma

Sophia A. Kolesnikova; Ekaterina G. Lyakhova; Anatoly I. Kalinovsky; Pavel S. Dmitrenok; Sergei A. Dyshlovoy; Valentin A. Stonik

doi:10.1071/CH08343

RESEARCH ARTICLE

Diterpenoid Hydroperoxides from the Far-Eastern Brown Alga Dictyota dichotoma

Sophia A. Kolesnikova ^A , Ekaterina G. Lyakhova ^A , Anatoly I. Kalinovsky ^A , Pavel S. Dmitrenok ^A , Sergei A. Dyshlovoy ^B and Valentin A. Stonik ^A ^C

+ Author Affiliations

- Author Affiliations

^A Far East Branch of the Russian Academy of Sciences, Pacific Institute of Bioorganic Chemistry, Vladivostok, Prospect 100 let Vladivostoku 159, 690022, Russia.

^B Far Eastern National University, Vladivostok, Sukhanova 8, 690950, Russia.

^C Corresponding author. Email: stonik@piboc.dvo.ru

Australian Journal of Chemistry 62(9) 1185-1188 https://doi.org/10.1071/CH08343
Submitted: 12 August 2008 Accepted: 2 March 2009 Published: 17 September 2009

Abstract

Two new compounds, dictyohydroperoxide 1 and hydroperoxyacetoxycrenulide 2, (Scheme 1) containing hydroperoxyl groups rarely found in algal terpenoids were isolated from the Russian population of brown alga Dictyota dichotoma. The known compounds acetoxycrenulide 4 and squalene were also found in this algal species for the first time. Some of the isolated compounds showed moderate cytoxicity against human cancer cell lines.

Acknowledgements

We acknowledge Grants RFBR N 08–04–00599-a, Grant of Supporting of the Leading Science Schools 2813.2008.4, Program of Presidium of RAS Molecular and Cell Biology, FEB RAS 09-III-B-05-154.

References

Diterpenoid Hydroperoxides from the Far-Eastern Brown Alga Dictyota dichotoma

Abstract

Acknowledgements

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