An Efficacious Protocol for the Oxidation of 3,4-Dihydropyrimidin-2(1H)-ones using Pyridinium Chlorochromate as Catalyst
Kamaljit Singh A B and Kawaljit Singh AA Organic Synthesis Laboratory, Department of Applied Chemical Sciences & Technology, Guru Nanak Dev University, Amritsar 143 005, India.
B Corresponding author. Email: kamaljit19in@yahoo.co.in
Australian Journal of Chemistry 61(11) 910-913 https://doi.org/10.1071/CH07432
Submitted: 15 December 2007 Accepted: 13 September 2008 Published: 5 November 2008
Abstract
4-Unsubstituted as well as 4,6-aryl/alkyl-3,4-dihydropyrimidin-2(1H)-ones were oxidized under neutral conditions using pyridinium chlorochromate to obtain the corresponding pyrimidin-2(1H)-ones in a synthetically useful manner.
Acknowledgements
We thank the UGC (31-53/2005/SR) and CSIR (01(1960)/04/EMR-II), New Delhi, for financial assistance.
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