Direct Measurement of Mechanical and Adhesive Properties of Living Cells Using Surface Forces Apparatus
Xavier Banquy A , Jean-Michel Rabanel A , Patrice Hildgen A and Suzanne Giasson A B CA Faculty of Pharmacy, Université de Montréal, C.P. 6128, Montréal, Québec H3C 3J7, Canada.
B Department of Chemistry, Université de Montréal, C.P. 6128, Montréal, Québec H3C 3J7, Canada.
C Corresponding author. Email: suzanne.giasson@umontreal.ca
Australian Journal of Chemistry 60(9) 638-645 https://doi.org/10.1071/CH07144
Submitted: 3 May 2007 Accepted: 3 August 2007 Published: 11 September 2007
Abstract
The adhesive and mechanical properties of living cells assembled into a monolayer on two different substrates were investigated using the surface forces apparatus (SFA) technique. The force measurements allowed elastic and bending moduli of the cells plated on substrates to be determined. The moduli are in good agreement with data reported in the literature for single cells determined using atomic force microscopy. Results confirm that the nature of the cell–substrate interactions can mediate cell mechanical and adhesive properties.
[1]
T. L. Sun,
D. Han,
K. Rhemann,
L. F. Chi,
H. Fuchs,
J. Am. Chem. Soc. 2007, 129, 149.
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
| Crossref | GoogleScholarGoogle Scholar |
