The Asymmetric Dihydroxylation of Some Alkenyl b-D-Glucopyranosides: the Preparation of an Optically Pure Episulfide

Abstract

The asymmetric dihydroxylation of various alkenyl tetra-O-acetyl- β-D-glucopyranosides has given mixtures of diols which, in one instance, has yielded a pure diastereoisomer upon recrystallization. This optically pure diol has been converted into an episulfide, a putative inhibitor of β-D-glucan hydrolases