
%0 Journal Article
%A Leenanuruksa, D 
%A McDowell, GH 
%T Experimental Diabetes in Lactating Sheep: Effects of Alloxan on Plasma Insulin, Glucose, Glucose Kinetics and Milk Characteristics
%J Australian Journal of Biological Sciences
%D 1988/06/01
%V 41
%N 2
%P 223-230
%K 
%R https://doi.org/10.1071/BI9880223
%U https://www.publish.csiro.au/paper/BI9880223 
%X After intravenous administration of alloxan (50 mg kg-1 liveweight) to lactating ewes, there were triphasic changes in plasma glucose and insulin. Almost immediately, plasma insulin decreased and hyperglycaemia occurred, then, between c. 5-12 h, insulin increased and ewes became hypoglycaemic. Thereafter, insulin decreased and glucose increased from c. 20 h after alloxan and the diabetic state was established. Changes in glucose production and utilization correlated with changes in plasma glucose. 
