
TY  - JOUR
A1  - Oakeshott, JG 
A1  - Chambers, GK 
A1  - East, PD 
A1  - Gibson, JB 
A1  - Barker, JSF 
T1  - Evidence for a Genetic Duplication involving Alcohol Dehydrogenase Genes in Drosophila huzzatii and Related Species
JF  - Australian Journal of Biological Sciences
JO  - Aust. Jnl. Of Bio. Sci.
Y1  - 1982
VL  - 35
IS  - 1
SP  - 73
EP  - 84
KW  - 
UR  - https://doi.org/10.1071/BI9820073 
N2  - Drosophila buzzatii has two closely linked loci (0· 4 ± O· 3 cM apart) encoding NAD + -dependent alcohol dehydrogenase. These two loci produce complex, non-overlapping electrophoretic phenotypes and differ in their ontogenetic expression, that of Adh-l relative to Adh-2 being less in adults than in third-instar larvae. Isozymes produced by the two Adh-2 alleles analysed have similar in vitro ADH activity levels, substrate specificities and thermostabilities, whereas the isozymes of the two Adh-l alleles examined differ in ADH activity and specificity for primary versus secondary alcohol substrates. 
ER  -

