
%0 Journal Article
%A O'Donnell, IJ 
%A Green, PE 
%A Connell, JA 
%A Hopkins, PS 
%T Immunization of Sheep With Larval Antigens of Lucilia cuprina
%J Australian Journal of Biological Sciences
%D 1981/09/01
%V 34
%N 4
%P 411-418
%K 
%R https://doi.org/10.1071/BI9810411
%U https://www.publish.csiro.au/paper/BI9810411 
%X Sheep were immunized with antigens extracted from third-instar larvae of L. cuprina. This procedure produced substantial titres of circulating antibody as measured by solid-phase radioimmunoassay or immunodiffusion or by both techniques. However, immunization did not confer protection against subsequent implant challenge with first-instar larvae. In vitro studies indicated that pooled sera from immunized sheep (mean immunodiffusion titre = 3) significantly reduced larval survival. Antigen specificity and the modulating effects of concomitant humoral responses to larval challenge are discussed in relation to the findings. 
