
%0 Journal Article
%A Oakeshott, JG 
%T Variation in the Direction of Selection Applied by Pentenol to the Alcohol Dehydrogenase Locus in Drosophila melanogaster
%J Australian Journal of Biological Sciences
%D 1977/05/01
%V 30
%N 3
%P 259-268
%K 
%R https://doi.org/10.1071/BI9770259
%U https://www.publish.csiro.au/paper/BI9770259 
%X This paper describes selective effects of pentenol-impregnated media on six genotypes at the alcohol dehydrogenase (Adh) locus in D. melanogaster. In the laboratory population studied, developmental times of pre-adults homozygous for an alcohol dehydrogenase 'null' allele increased with increasing pentenol concentrations. The developmental times of the other five genotypes, which produced active alcohol dehydrogenases, increased slightly at pentenol concentrations up to 0·0033%, but above this concentration they decreased markedly. In fact on 0·067% pentenol, the highest concentration tested, developmental times of these five genotypes were between 9 and 24 h less than their developmental times on media lacking penteno!. The magnitude of the reduction in developmental time differed significantly between genotypes and was positively correlated with alcohol dehydrogenase activity. 
