
TY  - JOUR
A1  - G Clark, Alan 
A1  - M Rogers, KarI 
T1  - Dependence upon Bile Volume of the Biliary Excretion of Bromocresol Green and Amaranth in the Anaesthetized Rat
JF  - Australian Journal of Biological Sciences
JO  - Aust. Jnl. Of Bio. Sci.
Y1  - 1975
VL  - 28
IS  - 4
SP  - 339
EP  - 352
KW  - 
UR  - https://doi.org/10.1071/BI9750339 
N2  - The kinetics of the biliary excretion of both bromocresol green and amaranth are better described in terms of rate equations that are functions of the cumulative volume of bile excreted rather than of time. The rate of disappearance of bromocresol green from the liver also appears to depend on the volume of bile excreted rather than on time. It is proposed that bromocresol green, and probably also amaranth, rapidly equilibrates between the hepatic and biliary compartments as a result of reabsorption from the biliary tree and that the rate-limiting factor in the biliary excretion of these dyes is the removal of dye from the biliary tree by bulk flow. 
ER  -

