
TY  - JOUR
A1  - Ralston, GB 
T1  - The Isolation of Aggregates of Spectrin From Bovine Erythrocyte Membranes
JF  - Australian Journal of Biological Sciences
JO  - Aust. Jnl. Of Bio. Sci.
Y1  - 1975
VL  - 28
IS  - 3
SP  - 259
EP  - 266
KW  - 
UR  - https://doi.org/10.1071/BI9750259 
N2  - Aggregated states of spectrin from bovine erythrocyte membranes can be detected in sedimentation velocity experiments. These aggregates have been isolated by means of gel filtration on columns of 4 % agarose. They appear to be stable over a wide range of pH and ionic strength, although they are dissociated by sodium dodecyl sulphate. Sedimentation equilibrium measurements yielded values of 960000 and 480000 for the molecular weights of the major aggregates, corresponding to a tetramer and dimer, respectively. The presence of different aggregated states in spectrin preparations may explain the wide variation in the reported physica~ properties of spectrin. 
ER  -

