
%0 Journal Article
%A M Gillespie, J 
%A Frenkel, MJ 
%T The Macroheterogeneity of Type I Tyrosine-rich Proteins of Merino Wool
%J Australian Journal of Biological Sciences
%D 1974/12/01
%V 27
%N 6
%P 617-628
%K 
%R https://doi.org/10.1071/BI9740617
%U https://www.publish.csiro.au/paper/BI9740617 
%X The cystine-poor family of tyrosine-rich proteins of wool as their S-carboxymethyl derivatives has been shown by chromatography on quaternary ammonium ethylcellulose (QAE-cellulose) at pH 10· 5 to consist of 10 groups of proteins which span a threefold range of tyrosine content and vary in many other amino acids, particularly S-carboxymethylcysteine. Electrophoresis at pH 8·9 revealed that most fractions contain two or more components and by further chromatography of five of these groups at pH 8·3 on DEAE-cellulose 10 components have been isolated. The amino acid composition suggests that the components within each QAE-cellulose group are very closely related. 
