
TY  - JOUR
A1  - Mead, RJ 
A1  - Segal, W 
T1  - Fluoroacetic acid Biosynthesis: a Proposed Mechanism
JF  - Australian Journal of Biological Sciences
JO  - Aust. Jnl. Of Bio. Sci.
Y1  - 1972
VL  - 25
IS  - 2
SP  - 327
EP  - 334
KW  - 
UR  - https://doi.org/10.1071/BI9720327 
N2  - A mechanism for the biosynthesis of fluoroacetic acid is presented. This is based on a correlation of phytochemical and taxonomic data together with the established function of pyridoxal phosphate in general amino acid metabolism. Evidence for this hypothesis is based on the reported incorporation of a wide range of synthetic nucleophiles into corresponding j3-substituted alanines by plant homo-genates. Fluoride ion is considered to be an acceptable nucleophile for a non-specific enzyme synthesizing a range of j3-substituted alanines, many of which occur in plants elaborating fluoroacetic acid. 
ER  -

