
%0 Journal Article
%A Strickland, WN 
%T Regulation of Glutamate Dehydrogenases in Neurospora Crassa as a Response to Carbohydrates and Amino Acids in the Media
%J Australian Journal of Biological Sciences
%D 1971/12/01
%V 24
%N 4
%P 905-916
%K 
%R https://doi.org/10.1071/BI9710905
%U https://www.publish.csiro.au/paper/BI9710905 
%X Mycelial pads of N. crassa grown for 48 hr in minimal medium were harvested, washed, and transferred to test media containing a variety of carbon and nitrogen sources. When some amino acids served as the sole carbon source, NAD-GDH was induced and the activity of NADP-GDH declined. Addition of sucrose depressed or prevented induction of NAD-GDH while NADP·GDH activity was maintained. Internal amino acid concentrations increased when mycelial pads were incubated in amino acids that induced NAD-GDH, but these accumulated amino acids were only oxidized in the absence of sucrose. The rate of amino acid accumulation decreased if sucrose was present in the media. 
