
TY  - JOUR
A1  - Weiss, DE 
T1  - Energy-Transducing Reaction in Biologyical Members. III. A Model of the Sodium Pump and Its Possible Relevance to Some Other Active Transport Processes
JF  - Australian Journal of Biological Sciences
JO  - Aust. Jnl. Of Bio. Sci.
Y1  - 1969
VL  - 22
IS  - 6
SP  - 1373
EP  - 1388
KW  - 
UR  - https://doi.org/10.1071/BI9691373 
N2  - A model of a sodium pump is presented which utilizes an alkali metal carrier in the form of a polypeptide "spring" containing about four consecutive phos-phatidylserine residues bound to lipid molecules embedded as a bilipid, rubber-like structure, attached to the matrix of a biological membrane. Electrostatic repulsive forces between the anions of the spring and osmosis, which are opposed by the elasticity of the bilipids, tend to maintain it in an expanded configuration of restricted dimensions, in which hydrated Na+ is preferred to K+ as a diffuse ionic atmosphere. Compression of the spring forms a helical structure in which unhydrated K+ is preferred to Na+ and is solvated by the oxygen atoms of carbonyl (or ether) groups within the peptide and the lipid. 
ER  -

