
TY  - JOUR
A1  - Roulston, WJ 
A1  - Schuntner, CA 
A1  - Schnitzerling, HJ 
T1  - Metabolism of Coumaphos in Larvae of the Cattle Tick Boophilus Microplus
JF  - Australian Journal of Biological Sciences
JO  - Aust. Jnl. Of Bio. Sci.
Y1  - 1966
VL  - 19
IS  - 4
SP  - 619
EP  - 634
KW  - 
UR  - https://doi.org/10.1071/BI9660619 
N2  - [82P]Coumaphos, a phosphorothionate, was rapidly absorbed and metabolized by cattle tick larvae dipped in aqueous suspensions of the acaricide. One metabolite was shown by chromatographic, spectroscopic, and cholinesterase inhibition evidence to be the oxygen analogue, a more potent in vitro cholinesterase inhibitor than the parent compound. Other water-soluble~ metabolites were only tentatively identified. Sublethal doses were metabolized mainly to water-soluble materials and a small quantity of oxygen analogue whereas lethal doses, producing complete mortality in 2-3 hr, yielded almost equal amounts of the oxygen analogue and water-soluble materials. 
ER  -

