
%0 Journal Article
%A Davern, CI 
%T The Inhibition and Mutagenesis of An Rna Bacteriophage By 5-Fluorouracil
%J Australian Journal of Biological Sciences
%D 1964/09/01
%V 17
%N 3
%P 726-737
%K 
%R https://doi.org/10.1071/BI9640726
%U https://www.publish.csiro.au/paper/BI9640726 
%X The yield of the RNA bacteriophage fCan 1 is strongly inhibited by 5.f1.uoro-uracil (FU). The production of non.infective phage particles in the presence of FU was demonstrated. The infective phage produced in the presence of FU have a relative plating efficiency lower than normal phage when assayed at supra-optimal temperatures, and FU was shown to be mutagenic for fean 1-Mutants sensitive to high temperature were isolated from infected cultures incubated in the presence of 2 X lQ-5M FIT. Complementation among these mutants could not be investigated because of strong interference preventing mixed infection. 
