Register      Login
Australian Journal of Biological Sciences Australian Journal of Biological Sciences Society
Biological Sciences
RESEARCH ARTICLE

Comparative Toxicities of Mimosine and Some Chemically Related Compounds to Mouse Bone Marrow Cells in Liquid Culture

MP Hegarty, CP Lee, GS Christie, FG De Munk and RD Court

Australian Journal of Biological Sciences 31(2) 115 - 122
Published: 1978

Abstract

Mimosine, a plant amino acid which is toxic in mammals, was shown to be a potent inhibitor of incorporation of [3H)thymidine in mouse bone marrow cells in liquid culture (> 70 % inhibition at a concentration of 2 x 10-4 M). To determine the parts of the molecule responsible for the inhibitory mechanism the effects of 13 chemically related compounds were examined in this system.

https://doi.org/10.1071/BI9780115

© CSIRO 1978

PDF (1.9 MB) Export Citation

Share

Share on Facebook Share on Twitter Share on LinkedIn Share via Email

View Dimensions