
TY  - JOUR
A1  - Westbrook, SL 
A1  - McDowell, GH 
T1  - Immunization of lambs against somatotropin release inhibiting factor to improve productivity: comparison of adjuvants
JF  - Australian Journal of Agricultural Research
JO  - Aust. J.  Agric. Res.
Y1  - 1994
VL  - 45
IS  - 8
SP  - 1693
EP  - 1700
KW  - adjuvants;immunization;SRIF;wool growth;liveweight gain;body compostion
UR  - https://doi.org/10.1071/AR9941693 
N2  - Responses to immunization against somatotropin release inhibiting factor (SRIF) were compared in lambs injected with SRIF plus either Freund's complete adjuvant (FCA), muramyl dipeptide (MDP), Freund's incomplete adjuvant/muramyl dipeptide (FIA/MDP), DEAE-Dextran (DEAE), or Quill A. By comparison with control lambs, immunized lambs grew faster and produced more wool. In lambs immunized with SRIF plus MDP or FIA/MDP, depths of back-fat and of the m. longissirnus dorsi were increased. Anti-SRIF antibody titres were very variable between groups of immunized lambs, with titres being highest for lambs injected with SRIF plus FCA or DEAE. Adverse effects of immunization were observed in lambs given FCA, DEAE and Quill A. It appears from the present study, that MDP alone or in combination with FIA would be suitable for use in commercial vaccines to enhance productivity by immunization against SRIF. 
ER  -

