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Australian Health Review Australian Health Review Society
Journal of the Australian Healthcare & Hospitals Association
RESEARCH ARTICLE

Red alert – a new perspective on patterns of blood use in the South Australian public sector

Rachel L. W. Allden A E , Romi Sinha A , David J. Roxby B , Susan Ireland A , Paul Hakendorf B and Kathryn L. Robinson C D
+ Author Affiliations
- Author Affiliations

A Department of Health (SA), Level 8, 11 Hindmarsh Square, Adelaide, SA 5000, Australia. Email: romi.sinha@health.sa.gov.au; susan.ireland@health.sa.gov.au

B Flinders Medical Centre, Flinders Drive, Bedford Park, SA 5042, Australia. Email: david.roxby@health.sa.gov.au; paul.hakendorf@health.sa.gov.au

C Australian Red Cross Blood Service, 301 Pirie Street, Adelaide, SA 5000, Australia. Email: krobinson@arcbs.redcross.org.au

D The Queen Elizabeth Hospital, 28 Woodville Road, Woodville South, SA 5011, Australia. Email: kathryn.robinson@health.sa.gov.au

E Corresponding author. Email: rachel.allden@health.sa.gov.au

Australian Health Review 35(3) 327-333 https://doi.org/10.1071/AH10957
Submitted: 23 August 2010  Accepted: 13 December 2010   Published: 25 August 2011

Abstract

Objectives. In 2006 South Australia had a red cell issue rate, measured as product issues per 1000 population, 22.4% higher than the national average. A pilot study was undertaken to investigate the disparity in issue rates between SA and the national average with a secondary aim of establishing information on SA red cell use.

Methods. A linked electronic database was developed using clinical, epidemiological and red cell transfusion data within hospitals in the SA public sector. Aggregated red cell use across the SA public health sector was analysed by clinical variables such as Diagnosis Related Group (DRG), including speciality related groups (SRGs) and major diagnostic categories (MDCs). The DRGs that were associated with blood use were identified and applied to national hospital separations data in order to derive comparative blood utilisation rates for SA and Australia.

Results. Although blood issue and usage by population measure showed a significant difference of 22.4 and 22.0% respectively between SA and Australia, when measured against weighted separations the differences reduced to 7.4 and 7.1% respectively.

Conclusion. This study showed the importance of analysing blood issues and utilisation on an activity adjusted basis rather than a raw per capita basis.

What is known about the topic? Transfusion practice can be monitored by various methods such as retrospective review of medical records and blood orders, prospective audits and analysis of blood usage by DRG classification. Blood utilisation studies have been used to describe the use of blood for a whole population or hospitals in order to understand the clinical reasons for transfusion. These studies also help to describe current practice, assess variability in practice and suggest areas where improvements in transfusion practice could be achieved.

What does this paper add? This study enabled an analysis of red cell usage in South Australia and the factors that can influence blood utilisation rates. This study also emphasised the fact that blood usage is better represented on a hospital activity basis rather than by raw population.

What are the implications for practitioners? The major implications for health practitioners would be the key findings related to red cell usage patterns. Firstly, older patients (>65 years) represented 36.5% of admissions and received 56.9% of the total red cells transfused. This has huge implications for future red cell use as an ageing population will both drive up demand and also result in a decreasing red cell donor pool. Secondly, high use of red cells in medical diagnoses such as haematology, medical oncology and gastroenterology confirms the current trend towards increasing use of red cells in medical diagnoses. This implies the need to focus on reducing reliance on blood use for medical patients and improve transfusion practice by regular audits, dissemination of guidelines and education.


References

[1]  Wells AW, Mounter PJ, Chapman CE, Stainsby D, Wallis JP. Where does blood go? Prospective observational study of red cell transfusion in north England. BMJ 2002; 325 803–4.
Where does blood go? Prospective observational study of red cell transfusion in north England.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BD38nhvV2mtA%3D%3D&md5=896c45972d89f48f5788779de3b9c2d3CAS |

[2]  Tinmouth A, Macdougall L, Fergusson D, Amin M, Graham ID, Hebert PC, et al Reducing the amount of blood transfused: a systematic review of behavioral interventions to change physicians’ transfusion practices. Arch Intern Med 2005; 165 845–52.
Reducing the amount of blood transfused: a systematic review of behavioral interventions to change physicians’ transfusion practices.Crossref | GoogleScholarGoogle Scholar |

[3]  Boralessa H, Goldhill DR, Tucker K, Mortimer AJ, Grant-Casey J. National comparative audit of blood use in elective primary unilateral total hip replacement surgery in the UK. Ann R Coll Surg Engl 2009; 91 599–605.
National comparative audit of blood use in elective primary unilateral total hip replacement surgery in the UK.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BD1MnptlOisA%3D%3D&md5=e6d36f21533276349c28aec83972120fCAS |

[4]  Brandis K, Richards B, Ghent A, Weinstein S. A strategy to reduce inappropriate red blood cell transfusion. Med J Aust 1994; 160 721–2.
| 1:STN:280:DyaK2c3mtFShuw%3D%3D&md5=93e9cd288a98896f13557eea6a82b466CAS |

[5]  French CJ, Bellomo R, Finfer SR, Lipman J, Chapman M, Boyce NW. Appropriateness of red blood cell transfusion in Australasian intensive care practice. Med J Aust 2002; 177 548–51.

[6]  Tuckfield A, Haeusler MN, Grigg AP, Metz J. Reduction of inappropriate use of blood products by prospective monitoring of transfusion request forms. Med J Aust 1997; 167 473–6.
| 1:STN:280:DyaK1c%2FlvFajsQ%3D%3D&md5=f470e68003554e13adc48a1012f3da80CAS |

[7]  Surgenor DM, Wallace EL, Churchill WH, Hao S, Hale WB, Schnitzer J. Utility of DRG and ICD-9-CM classification codes for the study of transfusion issues. Transfusions in patients with digestive diseases. Transfusion 1989; 29 761–7.
Utility of DRG and ICD-9-CM classification codes for the study of transfusion issues. Transfusions in patients with digestive diseases.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DyaK3c%2FntVWkug%3D%3D&md5=43ee979b03f1f6a2844574c492f395fdCAS |

[8]  Syrjälä MT, Kytöniemi I, Mikkolainen K, Ranimo J, Lauharanta J. Transfusion practice in Helsinki University Central Hospital: an analysis of diagnosis-related groups (DRG). Transfus Med 2001; 11 423–31.
Transfusion practice in Helsinki University Central Hospital: an analysis of diagnosis-related groups (DRG).Crossref | GoogleScholarGoogle Scholar |

[9]  Sekimoto M, Imanaka Y, Shirai T, Sasaki H, Komeno T, Lee J, et al Risk-adjusted assessment of incidence and quantity of blood use in acute-care hospitals in Japan: an analysis using administrative data. Vox Sang 2009; 98 538–46.

[10]  Jefferies LC, Sachais BS, Young DS. Blood transfusion costs by diagnosis-related groups in 60 university hospitals in 1995. Transfusion 2001; 41 522–9.
Blood transfusion costs by diagnosis-related groups in 60 university hospitals in 1995.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BD3MzisFGmtQ%3D%3D&md5=dedf664c5c6920215b6e13672d820999CAS |

[11]  Whyte GS, Brook CW. Suitability of casemix classification for output funding of blood services in Victoria. Victorian Blood Users Group. Med J Aust 1998; 169 415–8.
| 1:STN:280:DyaK1M%2FkvVSrsg%3D%3D&md5=41cbb57f263bb7e71c612af4241f2dafCAS |

[12]  BloodSafe. Government of South Australia, Department of Health; 2006. Available at http://www.health.sa.gov.au/bloodsafe/ [verified November 2010].

[13]  Classifications: AR-DRG Version 6.0. Commonwealth of Australia, Department of Health and Ageing; 2009. Available at http://www.health.gov.au/internet/main/publishing.nsf/Content/AR-DRG-Version_6.0 [verified July 2010].

[14]  Australian Refined Diagnosis Related Groups for admitted patients. In: Australian hospital statistics 2005–06. Cat. no. HSE 50. Canberra: Australian Institute of Health and Welfare; 2007. Available at http://www.aihw.gov.au/WorkArea/DownloadAsset.aspx?id=6442456901 [verified July 2010].

[15]  Data Collections. National Hospital Cost Data Collection (Round 10) 2005–2006 Peer Group Package Version 5.0. Commonwealth of Australia, Department of Health and Ageing; 2007. Available at http://www.health.gov.au/internet/main/publishing.nsf/Content/NHCDC-round10_peergroup [verified July 2010].

[16]  Chiavetta JA, Herst R, Freedman J, Axcell TJ, Wall AJ, van Rooy SC. A survey of red cell use in 45 hospitals in central Ontario, Canada. Transfusion 1996; 36 699–706.
A survey of red cell use in 45 hospitals in central Ontario, Canada.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DyaK28znsVeksQ%3D%3D&md5=9cf7aba8a0d984cd14fd12264640293fCAS |

[17]  Vamvakas EC, Taswell HF. Epidemiology of blood transfusion. Transfusion 1994; 34 464–70.
Epidemiology of blood transfusion.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DyaK2c3psFSmuw%3D%3D&md5=c1aa65f2761f00414fb036a3eb44820eCAS |

[18]  Wallis JP, Wells AW, Chapman CE. Changing indications for red cell transfusion from 2000 to 2004 in the North of England. Transfus Med 2006; 16 411–7.
Changing indications for red cell transfusion from 2000 to 2004 in the North of England.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BD28jis12qsw%3D%3D&md5=8c6036c825da3f72321a18d202ebec55CAS |

[19]  National Blood Authority. In: Cost provided by the National Blood Authority from analysis of total costs arising from the collection, testing, manufacturing, distribution and others incurred in the production of red cells by the Australian Red Cross Blood Service; 2010.

[20]  Monthly Supply Reports. National Blood Authority; 2006.

[21]  3222.0 – Estimated Resident Population December 2005. Australian Bureau of Statistics; 2010. Available at http://www.abs.gov.au/AUSSTATS/abs@.nsf/allprimarymainfeatures/8486924370CD6CB2CA2571EF007D51B2?opendocument [verified June 2011].

[22]  Australian hospital statistics 2005–06. Australian Institute of Health and Welfare; 2010. Available at http://www.aihw.gov.au/publication-detail/?id=6442467993 [verified June 2011].