Photosynthesis in health care? New thylakoid pigments complexation against cell death

Abstract

Plants and other photosynthetic organisms are particularly well adapted to resist the effect of Reactive Oxygen Species (ROS). With its 'Trapping and Turnover Mode Action', the formulated photosynthetically active plant extract (PCT-br1) is in fact a powerful natural product for targeting and neutralizing the ROS (Patent Pending). The quenching effect of PCT-br1 has both a high efficacy and a relatively long duration using the carotenoids to dissipate the energy as heat and to become ready to accept again the energy coming from triplet chlorophylls. PCT-br1 is therefore outstanding in the field of antioxidants; because of their capacity to regenerate their functional state, the organization of the pigments will permit a sustained anti-oxidative activity. Photosynthesis parameters are performed by pulse modulated chlorophyll fluorescence. PCT-br1 has an extremely important antioxidative efficacy; up to 88% of the oxidative stress generated by an oxydant (TBHP). Human neuroblastoma (IMR-32) and glial (C6 and C6Cx43) cell lines, which is known to respond to oxidative stress by apoptosis, was used as an in vitro cell model. The apoptotic protection of PCT-br1 acts for a very long period of time in pre-, co- and post treatment, and adapts its antioxidative action in relation of the amount of free radicals insult.