Reproductive technologies and genomic selection in dairy cattle
C. Ponsart A H , D. Le Bourhis A , H. Knijn B , S. Fritz C , C. Guyader-Joly D , T. Otter B , S. Lacaze E , F. Charreaux F , L. Schibler C , D. Dupassieux G and E. Mullaart B
+ Author Affiliations
- Author Affiliations
A UNCEIA Research and Development, 13 rue Jouet, 94704 Maisons Alfort, France.
B CRV, Wassenaarweg 20, 6843 NW Arnhem, The Netherlands.
C UNCEIA Research and Development, INRA GA, INRA - Domaine de Vilvert, 78352 Jouy en Josas, Paris, France.
D UNCEIA Research and Development, 484, Chemin Darefin, 38300 Chateauvillain, France.
E MIDATEST, domaine de Sensacq, 64230 Denguin, France.
F EVOLUTION, 69 rue de la Motte Brûlon, BP 30425, 35704 Rennes Cedex 7, France.
G UMOTEST, 259 route des Soudanières, CS 10002, 01250 Cezeyriat, France.
H Corresponding author. Email: claire.ponsart@unceia.fr
Reproduction, Fertility and Development 26(1) 12-21 https://doi.org/10.1071/RD13328
Published: 5 December 2013
Abstract
Genomic tools are now available for most livestock species and are used routinely for genomic selection (GS) in cattle. One of the most important developments resulting from the introduction of genomic testing for dairy cattle is the application of reasonably priced low-density single nucleotide polymorphism technology in the selection of females. In this context, combining genome testing and reproductive biotechnologies in young heifers enables new strategies to generate replacement and elite females in a given period of time. Moreover, multiple markers have been detected in biopsies of preimplantation stage embryos, thus paving the way to develop new strategies based on preimplantation diagnosis and the genetic screening of embryos. Based on recent advances in GS, the present review focuses on new possibilities inherent in reproductive technologies used for commercial purposes and in genetic schemes, possible side effects and beneficial impacts on reproductive efficiency. A particular focus is on the different steps allowing embryo genotyping, including embryo micromanipulation, DNA production and quality assessment.
Additional keywords: embryo genotyping, preimplantation diagnosis.
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