Pregnancy recognition and abnormal offspring syndrome in cattle
C. E. Farin A C , W. T. Farmer A and P. W. Farin B
+ Author Affiliations
- Author Affiliations
A Department of Animal Science, North Carolina State University, Raleigh, NC 27965-7621, USA.
B Department of Population Health and Pathobiology, North Carolina State University, Raleigh, NC 276061, USA.
C Corresponding author. Email: char_farin@ncsu.edu
Reproduction, Fertility and Development 22(1) 75-87 https://doi.org/10.1071/RD09217
Published: 8 December 2009
Abstract
Development of the post-hatching conceptus in ruminants involves a period of morphological expansion that is driven by complex interactions between the conceptus and its intrauterine environment. As a result of these interactions, endometrial physiology is altered, leading to establishment of the pregnancy and continued development of the placenta. Disruption of normal fetal and placental development can occur when embryos are exposed to manipulations in vitro or when inappropriate endocrine sequencing occurs in vivo during the pre- and peri-implantation periods. The present review addresses the development of the post-hatching bovine conceptus, its interactions with the maternal system and changes in development that can occur as a result of in vivo and in vitro manipulations of the bovine embryo.
Additional keywords: AIRN, embryo, fetus, in vitro production, insulin-like growth factor receptor 2.
Acknowledgements
The authors acknowledge the technical assistance of J. Eric Alexander and Jessica E. Hicks during the conduct of the authors’ work described herein. The authors’ research was supported by the North Carolina Agricultural Experiment Station, College of Veterinary Medicine and the Center for Comparative Medicine and Translational Research at North Carolina State University.
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