The Inclusion of Pyrrolizidine Alkaloids by α- and β-Cyclodextrins

Abstract

The association constants of α- and β- cyclodextrins with several pyrrolizidine alkaloids have been determined at pH 1.5 and 9.2 by using competitive spectrophotometry and solubility studies, respectively. Evidence of the nature of the pyrrolizidine alkaloids inclusion within the cyclodextrin cavity is presented.