DNA Binding Compounds. V. Synthesis and Characterization of Boron Containing Bibenzimidazoles Related to the DNA Minor Groove Binder, Hoechst-33258
DP Kelly, SA Bateman, RF Martin, ME Reum, M Rose and ARD Whittaker
Australian Journal of Chemistry
47(2) 247 - 262
Published: 1994
Abstract
The synthesis and characterization of four novel boron-containing bibenzimidazoles related to the DNA minor groove binder Hoechst 33258 are reported. Such compounds, particularly their 1°B-enriched forms, have potential as agents for boron neutron capture therapy which is used in the treatment of cancers.https://doi.org/10.1071/CH9940247
© CSIRO 1994