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Australian Journal of Chemistry Australian Journal of Chemistry Society
An international journal for chemical science
RESEARCH ARTICLE

Studies of Australian Ascidians. III. A New Tetrahydrocannabinol Derivative From the Ascidian Synoicum castellatum

AR Carroll, BF Bowden and JC Coll

Australian Journal of Chemistry 46(7) 1079 - 1083
Published: 1993

Abstract

Extracts of the colonial ascidian Synoicum castellatum have yielded four compounds derived from prenylated hydroquinones . These included a new tetrahydrocannabinol derivative (6), the first to be isolated from a marine source. Its structure was identified on the basis of one- and two-dimensional n.m.r. experiments at 300 MHz. The known quinone (3), the hydroquinone (4) and the chromene (5) were readily identified by spectral comparison with literature values. Cytotoxicity for (6) against a panel of cultured cell lines is reported.

https://doi.org/10.1071/CH9931079

© CSIRO 1993

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