Constituents of Eupomatia Species. xiv. The Structures of Eupomatilone-1, -2, -3, -4, -5, -6 and -7 Isolated From Eupomatia Bennettii

Abstract

On the basis of spectroscopic evidence, the eupomatilones (from eupomatilone-1 to -7) isolated from Eupomatia bennettii F. Muell. were shown to be degraded lignans . Eupomatilone-1 was assigned the structure (1), cis-4-methyl-3-methylene-5-(3″,4″,5″,6′-tetramethoxy-4′,5′-methylenedioxybiphenyl-2′-yl)dihydrofuran-2(3H)-one. The other six eupomatilones differ from eupomatilone-1 either in the degree of oxygenation of the biphenyl system or in the substitution of the furanone ring. Atropisomerism was observed with the compounds.