A Formal Total Synthesis of 3-O-Demethylfortamine
RC Cambie, ND Renner, PS Rutledge and PD Woodgate
Australian Journal of Chemistry
44(1) 61 - 75
Published: 1991
Abstract
p-Benzoquinone has been converted into the substituted cyclohexenone (11) in five steps and 33% overall yield by a Diels-Alder cycloaddition-cycloreversion approach in which anthracene functions as a protecting and stereodirecting group. The elaboration of (11) in four steps to the known epoxide (22) constitutes a formal total synthesis of 3-O-demethylfortamine (2).
https://doi.org/10.1071/CH9910061
© CSIRO 1991