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Australian Journal of Chemistry Australian Journal of Chemistry Society
An international journal for chemical science
RESEARCH ARTICLE

The Chemistry of Phthalide-3-carboxylic Acid. VII. Reaction With Isoquinoline Derivatives

C Donati, TV Hung and RH Prager

Australian Journal of Chemistry 43(2) 375 - 381
Published: 1990

Abstract

Phthalide-3-carboxylic acid has been decarboxylated in the presence of isoquinoline, 1-chloroisoquinoline and isoquinoline N-oxides to give low yields of compounds resulting from alkylation of the isoquinoline heterocycle at C1 with a phthalidyl group. Attempted Barton decarboxylation-alkylation in the presence of isoquinolinium salts was unsuccessful.

https://doi.org/10.1071/CH9900375

© CSIRO 1990

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