The Stereochemistry of Organometallic Compounds. XXXIV. Regioselection in the Hydroformylation of Silylalkenes

Abstract

The regiochemistry of hydroformylation of alkenes can be controlled by the use of bulky silyl groups attached to the alkene. Use of the t-butyldiphenylsilyl group leads to almost total regiocontrol and the method has been applied to the synthesis of aldols.