Reactions of (E)-1-Methoxy-1-trimethylsiloxyprop-1-ene with acyl isocyanates and acyl isothiocyanates

Abstract

Reaction of aryl acyl, and alkyl acyl isocyanates with (E)-1-methoxy-1-trimethylsiloxyprop-1-ene affords high yields of various methyl 3-acylamino-2-methyl-3-oxopropanoates. The corresponding acyl isothiocyanates give a variety of products depending on the structure of the isothiocyanate.