Thermodynamic properties of peptide solutions. The relative partial molar enthalpies of aqueous solutions of glycylglycylglycine, glycylglycylalanine and alanylglycylglycine

Abstract

The enthalpies of dilution at 298 K of aqueous solutions of the tripeptides glycylglycylglycine, glycylglycylalanine and alanylglycylglycine have been determined by flow microcalorimetry. From these data the partial molar enthalpies of the solvent in the solutions have been calculated. The results indicate that water side-chain interactions make an important contribution to the solvation of peptides.