Derivatives of Bicyclo[2,2,2]octane-2,6:3,5-dicarbolactone

Abstract

The reactions of the title dilactone with both acid and base are discussed. Evidence is presented for stable γ-lactones in the bicyclo[2,2,2]octane-2,6-carbolactone series. Epimerization α to hindered acid groups occurs under acetylating conditions to relieve steric strain in this system.