The alkaloids of Heliotropium curassavicum

Abstract

The main alkaloids of Heliotropium curassavicum Linn. have been identified. They are curassavine(4), an ester of trachelanthamidine with a new acid, curassavic acid [2-hydroxy-2-(1-hydroxyethyl)-3- methylpentanoic acid] (3), coromandaline (1), an ester of trachelanthamidine with (+)-viridifloric acid (previously unknown in nature), and heliovicine (2), an ester of trachelanthamidine with the uncommon (-)-enantiomer of trachelanthic acid.