Synthetic Plant Growth Regulators. The Synthesis of C-o-Carboxyphenyl Derivatives of Pyrimidine

Abstract

Synthetic routes to o-carboxyphenyl derivatives of pyrimidine, required for testing as potential plant growth regulators, are described. 2-(4-Phenylpyrimidin-2-yl)benzoic acid (3), 2-(2-phenylpyrimidin- 4-yl)benzoic acid (4) and 2-(2-phenylpyrimidin-5-yl)benzoic acid (5) were prepared by utilizing amide-acid chloride intermediates in the generation of the pyrimidine ring in each instance.