The Constituents of Rubus rosifolius. The Structure of Rosifoliol, a Biogenetically Significant Sesquiterpenoid

Abstract

Chemical investigation of the steam-volatile oil of the shrub Rubus rosifolius yielded pregeijerene (2), β-caryophyllene (3), humulene (4), dihydroagarofuran (5), an unidentified sesquiterpene ether, hedycaryol (6) and the novel epieudesmol rosifoliol for which structure (1) is proposed. The bio- genetic significance of these constituents and the carbon-13 magnetic resonance spectra of rosifoliol and related compounds are discussed.